7802 |
Multimammate rat, Mastomys natalensis, 16-month-old, female |
This animal was challenged with simian immunodeficiency virus, SIV, seven days prior to necropsy, and was started on 9-R-(2-phosphonomethoxypropyl)adenine (PMPA, or tenofovir) antiviral treatment a day after he was challenged with SIV. He was then found lethargic the day before necropsy, and found dead in his cage the following morning. A total of six days elapsed between initiation of the PMPA therapy and death of the animal. |